From immune complexity to a clinical decision

Unlocking Reliable Biomarkers
Surge's founders have spent a decade turning a high resolution readout of the patient's immune signatures into objective signals clinicians can act on.
We turn those signatures into solutions/products that help clinicians ground their decisions in objective data and deliver more personalized care to patients.
An End-to-End Platform for Reliable Biomarker Discovery
Our Process
01
Capture
Collection of patient samples and acquisition of high-dimensional biological data using state-of-the-art technologies such as CyTOF, Olink, and multiplex transcriptomics.
02
Decrypt
Integration and structuring of complex multiomic data through advanced AI/ML pipelines to reveal relevant biological signals and reduce dimensionality.
03
Identify
Extraction of robust, stable,and interpretable biomarkers signatures, using Stabl and ImmuneMind, our proprietary foundation models.
04
Translate
Development of clinically compatible assays based on the identified signatures, enabling applications in diagnostics, risk prediction, and personalized patient management.
From Data to Decisions
A state-of-the-art platform turning patients’ immune response into clinical actions.
At the core of Surge's technology are two models, Stabl and ImmuneMind. A high-resolution immune readout produces thousands of measurements.
Stabl identifies a sparse, reproducible set of markers that predicts outcomes, and preserves predictive performance across heterogeneous patient populations. Developed by our founders, themethod was the cover article of Nature Biotechnology in October 2024.
Stabl selects the signature, ImmuneMind reads it. Our proprietary single-cell model, pretrained on 1.1 billion immune cells, extracts cell level features from a standardized clinical panel and turns them into a patient-specific risk score. It learns the structure of the immune response and infers features that were not directly measured.
Its outputs can be interpreted at the level of the individual patient. ImmuneMind is developed under a data governance framework built for GDPR compliance and for the high-risk requirements that will applyto AI in medical devices under the EU AI Act. Clinical and cytometry data are managed for traceability, reproducibility, and multicentervalidation.

We’re Here to Help
Have a question, a request, or a comment? Let us know, and we'll be glad to talk it through with you.
